Allergy-inducing nickel in the casing of one of Apple's iPad models caused an 11-year-old boy to break out in an itchy body rash.
It is the latest example of people suffering reactions to the personal electronic devices which they use everyday.
Recent reports in medical journals show a rise in the number of instances of nickel allergies - partly due to better diagnosis, and partly due to how much we rely on gadgets containing nickel.
The unnamed boy was treated in a San Diego hospital, according to a report in the journal Pediatrics by dermatologist Sharon Jacob - after developing a scaly rash on his body.
While not life-threatening, the rashes can require steroid and antibiotic treatment if the skin eruptions become infected.
Doctors traced the cause of the outbreak to his iPad, after detecting a chemical compound found in nickel in the Apple device's outer coating.
The device was bought in 2010, meaning it was the original iPad model.
Apple has declined to say which of its other devices contain the material.
Dr Jacob said national data show that 25% of children who get skin tests for allergies have nickel allergies, compared to 17% a decade ago.
Common products such as eyeglass frames, zips and jewellery can also contain nickel.
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